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My subscription › Holtmore NattokinaseNattokinase 10,000 FUOne capsule. Your daily ritual.› Get to know the science.Explore the ingredient research → SHOP NATTOKINASE
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An older couple hiking on a mountain trail
4.8 from 1,119 reviews · 90,000+ customers

Clear Your Arteries.No Statin.

10,000 FU nattokinase dissolves the sticky fibrin your plaque is built on. Lab measured 10,400 FU. No side effects.

90,000+
Customers in 6 countries
36%
Less plaque in a 12-month study
5×
The dose on most natto bottles
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3rd Party Tested · 90-day money-back guarantee

CLEAR ARTERIES. NO STATIN.🇺🇸 MADE IN THE USA340+ PUBLISHED STUDIESLAB MEASURED 10,400 FU90,000+ CUSTOMERS90-DAY MONEY-BACK GUARANTEE

4 Reasons People Switch To Holtmore.

5× The Dose Most Bottles Sell.

Most natto bottles give you 2,000 FU. That's a maintenance dose. It barely touches plaque. You get the full 10,000 FU. In one capsule.

One capsule. Five times the power.

8 Heart Helpers. One Capsule.

Nattokinase clears the fibrin. CoQ10 puts back what statins drain. Aged garlic keeps arteries soft. Five more helpers ride along.

1 bottle instead of a shelf full

Every Batch Lab-Tested.

Big numbers are easy to print. Most “10,000 FU” bottles on Amazon have no lab report. We test every batch for real FU. Read the report yourself.

Label 10,000 FULab 10,400 FU ✓

Backed By A 1,062-Person Study.

Researchers tracked 1,062 people for 12 months. Plaque shrank 36%. Low doses did nothing. That's why we use 10,000 FU.

36% less plaque SEE THE STUDY ↗

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8 Ingredients. One Job: Clear, Open Arteries.

Most bottles give you one enzyme. Then they stop. This one doesn't.

Nattokinase · 500 mg · 10,000 FUDissolves the glue that holds plaque and clots together.

The enzyme from Japanese natto. It breaks down fibrin. The full 10,000 FU. Not 2,000.

CoQ10Heart fuel. Statins cut it in half. This puts it back.

Your heart runs on CoQ10. Statins can drain half of it in 30 days. That's the tired, achy feeling.

Aged GarlicThe garlic with real plaque evidence.

Even the skeptics on the forums agree on this one. It keeps arteries soft.

Turmeric RootCalms the swelling behind the plaque.

Swelling in the artery wall feeds plaque. Turmeric cools it down.

Dandelion RootFlushes out extra water and salt.

Less fluid means less push on your arteries.

Grape SeedGuards your blood vessel walls.

It keeps the walls strong and relaxed.

Bromelain · 10 mg · 2,400 GDU/gA second enzyme that breaks down fibrin.

It works next to nattokinase. Two enzymes. One job.

Pine Bark · 5 mgOpens your vessels. Cold, numb feet warm up.

Wider pipes. Warm hands and feet again.

Inside Every CapsuleOne capsule a day. That's the whole dose.

90 vegetarian capsules per bottle. No soy. Full label on the product page.

SEE THE FULL LABEL →

It's not your fault. No one told you what really clogs your arteries.

Over 35 million Americans are on a statin. Almost none were told about fibrin.

Your Plaque Has A Glue. Most Fixes Never Touch It.

11.5%

That's all a statin shrank plaque in 26 weeks. Nattokinase: 36.6%.

51%

Of your CoQ10, gone after 30 days on a statin. Your heart runs on it.

2,000 FU

The dose on most natto bottles. Too weak to clear plaque.

3,600 FU

Still did nothing in a 12-month study. It took 10,800.

The glue is called fibrin. We built Holtmore to dissolve it. ↓

Every 40 seconds, someone in the U.S. has a heart attack.

CDC

1 in 5 heart attacks is silent. You never feel it.

CDC

THE REAL CAUSE

It's Not Just Cholesterol. Meet Fibrin.

Your doctor never said fibrin. Your plaque is held together by a sticky web. It traps fat. It traps cells. It holds the clog in place. Statins don't touch it. Nattokinase dissolves it. The web breaks down. The plaque shrinks. Your blood flows again.

Clogged artery full of fibrin and plaque, then opening up, then clear with blood flowing
36%

Plaque shrank 36% in 12 months

1,062 people · 10,800 FU a day · Chen et al., Frontiers in Cardiovascular Medicine, 2022

3×

3× more plaque shrink than a statin

36.6% vs. 11.5% · 26 weeks · Ren et al., 2017

77.7%

77.7% got thinner, healthier artery walls

531 of 683 people · 12 months · Chen 2022

44.5%

Clot breakdown up 44.5% in 6 hours

One dose · Kurosawa et al., Scientific Reports, 2015

That's Why We Built Holtmore.

01 · WE DISSOLVE THE GLUE

Statins freeze plaque in place. Nattokinase breaks down the fibrin it sits on. The plaque loses its grip.

02 · WE PUT YOUR CoQ10 BACK

Statins drain it. Every capsule adds it back. So you stop feeling tired and old.

03 · ONE CAPSULE REPLACES THE CABINET

10,000 FU nattokinase. CoQ10. Aged garlic. Five more heart helpers. One bottle on the shelf instead of forty.

04 · THE DOSE THAT WORKED

Low doses failed in the study. You get 10,000 FU a day. Our lab measured 10,400.

Typical Natto Bottle vs. Holtmore

FeatureTypical natto bottleHoltmore
Dose per capsule2,000 FU10,000 FU
Capsules for 10,000 FU51
CoQ10 put back✗✓
8 heart helpers✗✓
Lab report you can readRarely✓ 10,400 FU measured
Soy in the capsuleOftenNone
Money-back windowVaries90 days
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Made In The USA. Tested Batch By Batch.

Most natto on Amazon is cheap Chinese powder with a big number on the label. Holtmore is made in the USA. In a cGMP facility. Every batch lab-tested. Non-GMO. No soy.

🇺🇸 Made in the USA

Label: 10,000 FU. Lab measured: 10,400 FU. ✓
Holtmore bottles on the filling line

90,000+ People. Real Results.

4.8 from 1,119 reviews · 97% rate it 4 or 5 stars

Susan K. with her Holtmore bottle
Susan K., 61, Ohio
★★★★★

My doctor asked what I changed.

Best numbers of my life. No statin. I did it on my own. I almost cried in that office. I'm not going to die like my dad did.

Tom R. with his Holtmore bottleCoronary calcium score letter in his car boot after a run
Tom R., 64, Charlotte
★★★★★

I'm a runner. My calcium score came back 383.

It scared me. Lean my whole life. Ate clean. This is the only thing I added. My rescan came back lower. My cardiologist asked what I changed.

Linda M. with her Holtmore bottle
Linda M., 58, Omaha
★★★★★

LDL 172 to 118. No statin.

Warm hands and feet again. My LDL went from 172 to 118 in four months. No statin. The tingling in my toes is gone. I take the stairs without stopping.

Dennis W. with his Holtmore bottle
Dennis W., 59, Indianapolis
★★★★★

Dad died of a heart attack.

I refuse to repeat his story. I check my numbers now. I take this every day. My blood pressure was 151/93. Eight weeks later it's 129/81. I'm finally doing something. Not just waiting.

Ray T. with his Holtmore bottle
Ray T., 66, Mesa
★★★★★

I was on 2,000 FU doing nothing.

I had taken nattokinase for years. The cheap stuff is a waste. 10,000 FU is a different thing. Three weeks in, my feet were warm at night. My cuff reading dropped 14 points.

Karen B. with her Holtmore bottle
Karen B., 63, Raleigh
★★★★★

I thought supplements were junk.

I have wasted money on pills that did nothing. So I was a skeptic. This is the first one that actually worked. LDL went from 191 to 139 in three months. No statin. The numbers don't lie.

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What Doctors Are Saying About Nattokinase

Real experts. Real research. Not a sales pitch.

Dr. Alan Reeves, MD holding a bottle of Holtmore Nattokinase
DOCTOR'S PICK
“I tell my patients this. Most nattokinase is underdosed. This is the full 10,000 FU — the dose the studies used. In one capsule. I recommend it for the heart.”
— Dr. Alan Reeves, MD
DOCTOR EXPLAINS

How nattokinase clears blocked arteries

An expert explains how nattokinase clears blocked arteries.

SPECIALIST

Nattokinase, clots and blood pressure

Same blood. Lower pressure. Clearer pipe.

THE DOSE

Why the dose matters

2,000 FU does nothing. 10,000 FU is the dose.

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Shipped To Your Door. In 6 Countries.

We ship to the USA, the UK, Ireland, Canada, Australia and New Zealand. Your Holtmore is made in the USA and ships from the USA. Tracked from our door to yours.

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Ships out within 1–2 business days

90 Days. 100% Money Back.

Better numbers at your next checkup. Or every dollar back.

Lab-Tested

We test every batch. Label 10,000 FU. Lab 10,400 FU.

90-Day Guarantee

Take Holtmore for 90 days. Numbers didn't move? Email us. You get every dollar back. No questions asked. The only risk is doing nothing.

Real People. Fast Answers.

Questions? Email support@holtmore.com. We answer 7 days a week, usually within 24 hours.

The real risk is the plaque that keeps building.

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Join 90,000+ Holtmore customers.

Heart tips and first dibs on every new batch.

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